Modafinil stimulates human nervous system and same as any other stimulant can have a number of side effects, such as headache, insomnia, and nervousness. However, they occur on a seldom basis.
Modafinil was discovered in 1973; the studies were conducted in France. Experiments showed that even after taking a modafinil dosage, which is 10 times larger than recommended – 4500 mg – healthy individuals didn’t show modafinil side effects. Moreover, they even showed no hemodynamic changes of the heart contraction frequency or increase of blood pressure. The data was published in 1991 in a number of medical magazines.
Then, clinical researches on human use safety were continued in the USA, which is a usual practice. As a rule, all medical drugs, which are planned to be sold in the USA territory, are researched additionally with the purpose to widen and verify the information. Modafinil side effects were detected through gradual modafinil dosage increase. Researches featured men of 18 to 50 years of age, who didn’t have any physical or psychical aberrations recorded. In the end, exceeding the recommended daily modafinil dose of 400 mg two times, upon taking modafinil dosage of 800 mg, two volunteers showed increased heart contraction frequencies and rise of blood pressure. However, modafinil side effects quickly passed after the reduction of modafinil dosage.
As a result, it was discovered that modafinil side effects can appear if a person will take the highest daily modafinil dose of 400 mg for the course of several days. This is due to the fact that modafinil removes the need for sleep, and promotes removal of fatigue and intensification of mental activity, although the organism has to be provided with rest. Modafinil side effects pass after the stoppage of medicine use and/or after the reduction of modafinil dosage.